Sunday, November 15, 2026

Peer-Reviewed Clinical Evidence Platform

The research that matters, without the jargon.

Peer-reviewed breakthroughs in plain English alongside verified outcomes, evidence grades, and clinical study details for everyone from everyday readers to medical students.

ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

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Showing 34 briefings

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Pulmonology

Pulmonology Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

PULMONOLOGY · CLINICAL PRACTICE

Mediastinal Mass With Recurrent Hemorrhagic Pleural Effusion

Empirical antituberculosis therapy also was given, but no definitive diagnosis was established. A 55-year-old man was admitted with a 2-year history of recurrent dyspnea and exertional breathlessness, accompanied by intermittent blood-tinged sputum.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readChestNov 15, 2026

PULMONOLOGY · CLINICAL PRACTICE

Bilateral Pulmonary Nodules After Lung Transplantation: A Rare Diagnosis

He was also placed on mycophenolic acid, which was soon held because of neutropenia. Antibody-mediated rejection was successfully treated with our institutional multimodal regimen, including a combination of plasmapheresis, carfilzomib, and anti-thymocyte globulin followed by monthly IV immunoglobulin and tocilizumab injections.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readChestNov 15, 2026

PULMONOLOGY · CLINICAL PRACTICE

A Young Man With Hypereosinophilia and Pseudochylothorax

There was no other significant environmental history. The patient received anti-tubercular therapy along with tapering corticosteroids, showing initial clinical improvement.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readChestNov 15, 2026

PULMONOLOGY · REAL-WORLD COHORT

Optimizing Sepsis Time Zero Definitions Through Associations between Antibiotic Timing and Mortality

Risk of death associations with antibiotics beyond 1 hour were most evident when sepsis time zero was defined by hypotension or lactate ≥4.0mmol/L, and with antibiotics beyond 3 hours when defined by acute respiratory failure. These findings could inform refinements to sepsis time zero definitions to better guide antibiotic urgency and performance measurement.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readAmerican Journal of Respiratory and Critical Care MedicineNov 12, 2026

PULMONOLOGY · REAL-WORLD COHORT

Pragmatic Clinical indicators of Tuberculosis Transmission Risk: a Household Contact Cohort Study

Our results show that in this large household cohort, cavitary extent on chest radiograph and cough duration in people with TB were associated with increased TB transmission risk and showed dose-response relationships with TB infection. These simple, readily available indicators may help target preventive interventions in high-burden settings; however, associations with incident TB remain uncertain.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readChestNov 11, 2026

PULMONOLOGY · PHASE III

Longitudinal change in FEV 1 in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor in France: a prospective observational study

These results suggest that about a third of adults with cystic fibrosis (tissue scarring) who are treated with ETI had a persistent decline in ppFEV 1 . These data emphasise the importance of regular ppFEV 1 monitoring and highlight the need to improve current therapeutic strategies to prevent ppFEV 1 decline.

5/5 Gold Standard

Evidence Meter · 5/5

Gold-Standard Human Evidence

Backed by randomized controlled human trials or a formal meta-analysis pooling multiple clinical studies.

1 min readThe Lancet Respiratory MedicineNov 11, 2026

PULMONOLOGY · REAL-WORLD COHORT

Consensus on the definition, components, and grading of composite postoperative pulmonary complication outcomes (PrECiSIOn): insights from an international Delphi expert panel

Further work should focus on external validation, implementation in clinical trial analyses, and assessment of applicability across diverse patient populations and health-care settings. Panellists supported the use of routinely collected clinical data and a standardised in-hospital monitoring approach but did not reach consensus on the optimal follow-up period or need for post-discharge surveillance.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readThe Lancet Respiratory MedicineNov 11, 2026

PULMONOLOGY · REAL-WORLD COHORT

Associations between temperatures, extreme temperature events, and onset of acute exacerbations of COPD: a time-stratified case-crossover study in China

Lower temperature and extreme cold events, particularly CCS, were associated with AECOPD onset. Symptom-onset timing may better capture temperature-related associations than admission timing.

4/5 Strong Trial

Evidence Meter · 4/5

Strong Clinical Evidence

Tested directly in patients through a prospective clinical trial or large multicenter human cohort.

1 min readChestNov 11, 2026

PULMONOLOGY · REAL-WORLD COHORT

Heart Transplant for Advanced Heart Failure: A Review

Heart transplant is the definitive therapy for carefully selected patients with advanced heart failure despite receiving optimal, guideline-directed therapy. After heart transplant, lifelong multidisciplinary care is necessary to manage immunosuppression, prevent and treat rejection and cardiac allograft vasculopathy, and monitor for infection and malignancy.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readJAMANov 10, 2026

PULMONOLOGY · REAL-WORLD COHORT

Obstructive sleep apnoea: an overlooked challenge in the current NHS Strategy

Implementation should be phased and evaluated prospectively for clinical outcomes, equity, workforce requirements, affordability, and budget impact. A proportionate NHS response should prioritise targeted case-finding within existing chronic-disease pathways, access to validated home-based diagnostics, specialist capacity for complex disease, and sustained treatment support.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readThe Lancet Respiratory MedicineNov 10, 2026

PULMONOLOGY · REAL-WORLD COHORT

Systemic Inflammation in Bronchiectasis: Data from the EMBARC-BRIDGE Study

Bronchiectasis is associated with a systemic neutrophil and endothelial (blood-vessel lining) inflammatory signature linked to disease severity and risk of severe exacerbations, alongside altered but functionally-responsive circulating neutrophils. Neutrophilic inflammation in the airways is associated with exacerbation risk in patients with bronchiectasis.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readAmerican Journal of Respiratory and Critical Care MedicineNov 7, 2026

PULMONOLOGY · REAL-WORLD COHORT

Development and Validation of a Pre-COPD Score to Predict Incident COPD

The pre-COPD score is useful in predicting the onset of COPD with clinically relevant discrimination in three cohorts with different risk profiles. To test the hypothesis that development of COPD can be predicted by characterizing pre-COPD and creating a simple pre-COPD score.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readAmerican Journal of Respiratory and Critical Care MedicineNov 6, 2026

Showing 12 of 34 medical briefings

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