Navigate peer-reviewed breakthroughs by pharmacological class, genetic target, circulating biomarker, or diagnostic modality. Select any clinical entity to inspect all linked studies.
Everyday Health & Science Hubs
Indexed Entities (24)
Drug / Therapy4 Peer-Reviewed Briefings
mRNA Vaccines & Therapeutics
Lipid-nanoparticle messenger RNA neoantigen vaccines and protein-replacement platforms.
Active Specialties:ImmunologyOncologyEndocrinology
In a recent issue of Nature, macrophages polarized to an inflammatory state were found to produce several chimeric RNAs through trans-splicing with consequences for the inflammatory response. Published in Immunity, these peer-reviewed immunology findings provide quantitative evidence to inform clinical risk stratification, therapeutic decision-making, and follow-up trial design.
3/5 Observational
Evidence Meter · 3/5
Real-World Observation
Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.
The data were presented at the ESMO Congress 2026, held October 23-27, in Madrid, Spain. Published in Cancer discovery, these peer-reviewed oncology findings provide quantitative evidence to inform clinical risk stratification, therapeutic decision-making, and follow-up trial design.
5/5 Gold Standard
Evidence Meter · 5/5
Gold-Standard Human Evidence
Backed by randomized controlled human trials or a formal meta-analysis pooling multiple clinical studies.
Researchers argue the vaccines themselves are working, and that success will depend on testing them in the right patients and settings and judging them by overall survival rather than tumor progression. Published in Cancer discovery, these peer-reviewed oncology findings provide quantitative evidence to inform clinical risk stratification, therapeutic decision-making, and follow-up trial design.
4/5 Strong Trial
Evidence Meter · 4/5
Strong Clinical Evidence
Tested directly in patients through a prospective clinical trial or large multicenter human cohort.
This nutrient-sensing mechanism regulates immunity in colorectal cancer and viral infection while revealing new opportunities for therapeutic intervention. How nutrients shape gene expression has remained a fundamental question.
3/5 Observational
Evidence Meter · 3/5
Real-World Observation
Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.
1 min read·Cell Metabolism·
Patient & Student Companion
Everyday Lab & Drug Translator
Instant plain-English guides for common blood tests and prescriptions—what normal ranges mean, what high/low values signal, and what to ask your clinician.
Lab Marker3-Month Blood Sugar
HbA1c
Measures the percentage of red blood cell hemoglobin coated with glucose over roughly 90 days.
Normal: below 5.7% · Prediabetes: 5.7%–6.4%
6.5% or higher on two tests diagnoses diabetes; very low values can occur alongside hypoglycemia or hemolytic anemia.
Ask your doctor: “Does my HbA1c match my daily fasting/post-meal glucose trends?”
Estimated glomerular filtration rate—how many milliliters of blood your kidneys filter every minute.
Healthy adult filter rate: 90+ mL/min/1.73m²
Values persistently below 60 for 3+ months (or elevated urine albumin) mark chronic kidney disease; single dips can simply reflect dehydration or NSAID use.
Ask your doctor: “Should we pair eGFR with a urine albumin-to-creatinine test (uACR)?”