3 Key Takeaways
Plain English Summary- 01Core Finding
Delivered via viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary, this clinical practice approach targets Immune response.
- 02Study Evidence
Study design used a clinical evidence review protocol to track clinical outcomes.
- 03Practical Meaning
Benefits and risks vary by individual health history — discuss with a healthcare professional.
What This Means for You
Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.
The Discovery
To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons. Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed.
How It Works, Simply
This infectious disease research focuses on immune response. Researchers evaluated it using a standard-of-care clinical practice · Clinical evidence review at the clinical practice stage of medical research.
3 Key Takeaways
Clinical Takeaways- 01Core Finding
Delivered via viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary, this clinical practice approach targets Immune response.
- 02Study Evidence
Study design used a clinical evidence review protocol to track clinical outcomes.
- 03Practical Meaning
Benefits and risks vary by individual health history — discuss with a healthcare professional.
Biological Mechanism & Study Design
Study Design & Cohort
Clinical evidence review
Standard-of-care clinical practice · Clinical evidence review · Clinical Practice
Biological Pathway & Modality
Immune response
Intervention: Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary
Experimental Findings & Endpoints
To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons.
Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed.
Clinical Translation & Practice Context
Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.
The Bottom Line · Clinical Pearl
“Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.”
Published in The Journal of Infectious Diseases · Current Stage: Clinical Practice