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ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

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Showing 2 briefings matching “inflammation”

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Nephrology

Nephrology Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

NEPHROLOGY · CLINICAL PRACTICE

Microvascular inflammation in kidney transplants: finally an effective treatment?

As demonstrated in a study in this issue of Kidney International, targeting CD38, a glycoprotein expressed on both plasma cells and natural killer cells, shows great promise in treating microvascular inflammation in kidney transplants. Microvascular inflammation-glomerulitis and peritubular capillaritis-is the hallmark histologic lesion of antibody-mediated allograft rejection and may also occur in the absence of donor-specific antibodies.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readKidney InternationalNov 8, 2026

NEPHROLOGY · PRECLINICAL

Peritoneal dialysis induces hepatic metabolic stress as an instigator for systemic inflammation

Ours study found chronic hepatic metabolic stress induced by PD. Healthy mice and mice with chronic kidney disease (5/6 nephrectomy C57BL/6 aged 12-14 weeks) underwent seven weeks of PD.

2/5 Preclinical

Evidence Meter · 2/5

Animal & Preclinical Data

Demonstrated in living animal models before large-scale human safety and dosing trials begin.

1 min readKidney InternationalOct 20, 2026

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