The research that matters, without the jargon.

Peer-reviewed breakthroughs in plain English alongside verified outcomes, evidence grades, and clinical study details for everyone from everyday readers to medical students.

ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

Health Hubs:

Stage: Evidence:

Showing 3 briefings matching “inflammation”

Reset all filters

Infectious Disease

Infectious Disease Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

INFECTIOUS DISEASE · PRECLINICAL

Biological Sex as a Determinant of Neurological Outcomes During Zika Virus Infection

Our findings demonstrate that sexually dimorphic immune responses contribute to increased male susceptibility to virus-induced neuropathology. Using a mouse model of Zika virus infection, we find that males develop more severe clinical disease compared to females, despite comparable infectious viral loads.

2/5 Preclinical

Evidence Meter · 2/5

Animal & Preclinical Data

Demonstrated in living animal models before large-scale human safety and dosing trials begin.

1 min readThe Journal of Infectious DiseasesNov 5, 2026

INFECTIOUS DISEASE · PHASE I/II

Long-term Outcomes in Previously Healthy non-HIV Individuals with Cryptococcal Meningitis Treated with Pulse-taper Corticosteroids for Post-infectious Inflammatory Syndrome

In immunocompetent patients with CM-PIIRS, adjunctive corticosteroid therapy was associated with sustained improvement in neurologic, visual, and radiologic outcomes with mixed improvement in hearing after a year of therapy, with mild residual deficits. Post-infectious inflammatory response syndrome (PIIRS) is an increasingly recognized complication of cryptococcal meningoencephalitis (CM) in non-HIV infected hosts with significant morbidity and risk of death.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readThe Journal of Infectious DiseasesOct 12, 2026

INFECTIOUS DISEASE · REAL-WORLD COHORT

Plasma Proteome Signature of Immune Inhibition is Associated with Cytomegalovirus in People with HIV-1

These data identify a CMV-associated plasma proteomic signature in treated HIV, characterized by immunoinhibitory/cytotoxic programs, supporting targeting CMV to reduce immune dysregulation and related comorbidities in PWH. Cytomegalovirus (CMV) is highly prevalent and associated with comorbidities in people with HIV-1 (PWH).

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readThe Journal of Infectious DiseasesOct 7, 2026

Interactive Fact Check