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ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

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Showing 3 briefings matching “inflammation”

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Cardiology

Cardiology Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

CARDIOLOGY · REAL-WORLD COHORT

Assessment of Coronary Inflammatory Risk From Noncontrast Cardiac Computed Tomography

Per the results of this cohort study, NC FAI score provides prognostic performance comparable to CCTA FAI score and improves cardiovascular risk prediction and reclassification beyond CAC score. Elevated FAI score, derived from either CCTA or NCCT, should be interpreted as a risk-enhancing factor that may prompt intensification of established, evidence-based preventive measures and may serve as a potential future gatekeeper for the use of targeted anti-inflammatory treatments.

4/5 Strong Trial

Evidence Meter · 4/5

Strong Clinical Evidence

Tested directly in patients through a prospective clinical trial or large multicenter human cohort.

1 min readJAMA CardiologyNov 11, 2026

CARDIOLOGY · REAL-WORLD COHORT

Inflammation and early atherosclerosis beyond traditional risk factors: an imaging study

Inflammation contributes to SA burden, as assessed by direct plaque quantification, beyond the effects of LDLc and SBP. These findings indicate that inflammation, captured through the use of systemic inflammatory markers, is a risk factor relevant across the entire continuum of atherosclerosis, exerting a deleterious impact comparable to that of LDLc and SBP.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readEuropean Heart JournalNov 10, 2026

CARDIOLOGY · REAL-WORLD COHORT

Sacubitril/valsartan for radiation-induced heart disease in children: preclinical and clinical findings

This first-in-kind translational study demonstrates that early prophylaxis with sacubitril/valsartan is a feasible and effective strategy to mitigate radiation-induced cardiotoxicity in children. These findings, underpinned by multi-modal validation from bench to bedside, challenge the reactive management paradigm in paediatric cardio-oncology and establish a foundational evidence base for a new standard of proactive heart care in childhood cancer survivors.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readEuropean Heart JournalNov 10, 2026

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