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ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

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Showing 4 briefings matching “depression”

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Neurology

Neurology Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

NEUROLOGY · REAL-WORLD COHORT

Clinical Risk Factors for Suicide in Persons With Epilepsy: A Nationwide Population-Based Case-Control Study

This study identified a distinct risk profile for suicide in persons with epilepsy, highlighting alcohol and substance abuse, living... The stronger associations for substance abuse may reflect characteristics specific to epilepsy populations and the focus on completed suicide.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readNeurologyNov 15, 2026

NEUROLOGY · REAL-WORLD COHORT

Network disruption in post-stroke depressive symptoms: a Bayesian multicohort study

Depressive symptoms were most strongly associated with right frontal lesions and right-dominant structural disconnection in frontal cortico-subcortical circuits. Lesion associations were found in clusters in the right hemisphere including cortical (frontal, insular, parietal) and subcortical regions (striatum, amygdala, hippocampus) and adjacent white matter.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readBrain: A Journal of NeurologyNov 6, 2026

NEUROLOGY · REAL-WORLD COHORT

Prediction of First and Recurrent Falls in Parkinson's Disease

Clinical measures may identify next-year fall risk in PD with moderate discrimination, although performance attenuated in external validation. Exploratory biomarkers provided modest incremental value in development but not in external validation.

3/5 Observational

Evidence Meter · 3/5

Real-World Observation

Finds meaningful patterns in human health records or cohorts, though observational data cannot prove direct cause.

1 min readAnnals of NeurologyOct 30, 2026

NEUROLOGY · RANDOMIZED CLINICAL TRIAL

Internet Intervention for Functional Seizures: A Randomized Clinical Trial

Results of this randomized clinical trial show that in adults with FS, a self-guided internet-based intervention reduced seizure frequency and improved anxiety relative to standard care, offering a scalable option for patients unable to access specialist psychological care. Functional seizures (FS) are a common and disabling presentation in neurology clinics, but evidence-based treatments are difficult to access in Australia and in many regions globally.

5/5 Gold Standard

Evidence Meter · 5/5

Gold-Standard Human Evidence

Backed by randomized controlled human trials or a formal meta-analysis pooling multiple clinical studies.

1 min readJAMA NeurologyOct 26, 2026

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