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ClearMed Editorial Digest500 briefings across 12 specialties121 Phase III & clinical practice

Indexed from PubMed, NEJM, The Lancet, JAMA, Nature MedicineSaved Library

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Endocrinology

Endocrinology Clinical Briefings

Peer-Reviewed Clinical Digests · Verified Scientific Media

ENDOCRINOLOGY · REAL-WORLD COHORT

Clinical and metabolic subtypes of recent-onset adult type 1 diabetes: a prospective cohort study

Our results indicate that individuals with combined autoimmunity and lower insulin sensitivity present with clinical diabetes earlier than classic type 1 diabetes along the β-cell decline trajectory, identifying a potential timeframe for disease-modifying interventions in specific type 1 diabetes subtypes. Adult-onset type 1 diabetes exhibits substantial heterogeneity.

4/5 Strong Trial

Evidence Meter · 4/5

Strong Clinical Evidence

Tested directly in patients through a prospective clinical trial or large multicenter human cohort.

1 min readThe Lancet Diabetes & EndocrinologyOct 30, 2026

ENDOCRINOLOGY · RANDOMIZED CLINICAL TRIAL

Real-world, digital-first delivery of GLP-1 receptor agonist therapy in women

Interpretation is limited by the observational design, absence of a comparator group, self-pay population and 6-month follow-up. These findings support the feasibility of delivering structured, digitally enabled obesity pharmacotherapy at scale and provide prospective real-world implementation evidence for this care model.

5/5 Gold Standard

Evidence Meter · 5/5

Gold-Standard Human Evidence

Backed by randomized controlled human trials or a formal meta-analysis pooling multiple clinical studies.

1 min readNature MedicineOct 16, 2026

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